Small Molecule Tyrosine Kinase Inhibitor Nintedanib Reduces Development of Cardiac Allograft Vasculopathy in Murine Aortic Allografts

BACKGROUND: Nintedanib is a small molecule tyrosine kinase inhibitor that blocks the action of the platelet-derived growth factor receptor (PDGFR), the vascular endothelial growth factor receptor (VEGFR) and the fibroblast growth factor receptor. All of these receptors have been shown to be involved...

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Detalles Bibliográficos
Autores principales: Gocht, Annika, Spriewald, Bernd, Distler, Jörg H.W., Ramsperger-Gleixner, Martina, Ensminger, Stephan M., Weyand, Michael, Heim, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056280/
https://www.ncbi.nlm.nih.gov/pubmed/30046657
http://dx.doi.org/10.1097/TXD.0000000000000804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056280/
https://www.ncbi.nlm.nih.gov/pubmed/30046657
http://dx.doi.org/10.1097/TXD.0000000000000804

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