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Small Molecule Tyrosine Kinase Inhibitor Nintedanib Reduces Development of Cardiac Allograft Vasculopathy in Murine Aortic Allografts
BACKGROUND: Nintedanib is a small molecule tyrosine kinase inhibitor that blocks the action of the platelet-derived growth factor receptor (PDGFR), the vascular endothelial growth factor receptor (VEGFR) and the fibroblast growth factor receptor. All of these receptors have been shown to be involved...
Autores principales: | Gocht, Annika, Spriewald, Bernd, Distler, Jörg H.W., Ramsperger-Gleixner, Martina, Ensminger, Stephan M., Weyand, Michael, Heim, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056280/ https://www.ncbi.nlm.nih.gov/pubmed/30046657 http://dx.doi.org/10.1097/TXD.0000000000000804 |
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