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Schizophrenia-related dysbindin-1 gene is required for innate immune response and homeostasis in the developing subventricular zone

Schizophrenia is a neurodevelopmental disorder likely caused by environmental and genetic risk factors but functional interactions between the risk factors are unclear. We tested the hypothesis that dysbindin-1 (Dtnbp1) gene mutation combined with postnatal exposure to viral mimetic polyI:C results...

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Detalles Bibliográficos
Autores principales: Al-Shammari, Abeer R., Bhardwaj, Sanjeev K., Musaelyan, Ksenia, Srivastava, Lalit K., Szele, Francis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056426/
https://www.ncbi.nlm.nih.gov/pubmed/30038210
http://dx.doi.org/10.1038/s41537-018-0057-5