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Exposure to galactic cosmic radiation compromises DNA repair and increases the potential for oncogenic chromosomal rearrangement in bronchial epithelial cells

Participants in deep space missions face protracted exposure to galactic cosmic radiation (GCR). In this setting, lung cancer is a significant component of the overall risk of radiation-exposure induced death. Here we investigate persistent effects of GCR exposure on DNA repair capacity in lung-deri...

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Detalles Bibliográficos
Autores principales: Li, Z., Jella, K. K., Jaafar, L., Li, S., Park, S., Story, M. D., Wang, H., Wang, Y., Dynan, W. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056477/
https://www.ncbi.nlm.nih.gov/pubmed/30038404
http://dx.doi.org/10.1038/s41598-018-29350-5