Overexpression of PEAK1 contributes to epithelial–mesenchymal transition and tumor metastasis in lung cancer through modulating ERK1/2 and JAK2 signaling

Pseudopodium-enriched atypical kinase 1 (PEAK1), a novel non-receptor tyrosine kinase, has been demonstrated to act as an oncogenic regulator in breast and pancreatic cancers. However, the role of PEAK1 in the progression and metastasis of lung cancer is still unknown. Here, we observed that ectopic...

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Detalles Bibliográficos
Autores principales: Ding, Chenbo, Tang, Wendong, Fan, Xiaobo, Wang, Xiyong, Wu, Hairu, Xu, Hongbo, Xu, Wei, Gao, Wei, Wu, Guoqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056550/
https://www.ncbi.nlm.nih.gov/pubmed/30038287
http://dx.doi.org/10.1038/s41419-018-0817-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056550/
https://www.ncbi.nlm.nih.gov/pubmed/30038287
http://dx.doi.org/10.1038/s41419-018-0817-1

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