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Overexpression of PEAK1 contributes to epithelial–mesenchymal transition and tumor metastasis in lung cancer through modulating ERK1/2 and JAK2 signaling
Pseudopodium-enriched atypical kinase 1 (PEAK1), a novel non-receptor tyrosine kinase, has been demonstrated to act as an oncogenic regulator in breast and pancreatic cancers. However, the role of PEAK1 in the progression and metastasis of lung cancer is still unknown. Here, we observed that ectopic...
Autores principales: | Ding, Chenbo, Tang, Wendong, Fan, Xiaobo, Wang, Xiyong, Wu, Hairu, Xu, Hongbo, Xu, Wei, Gao, Wei, Wu, Guoqiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056550/ https://www.ncbi.nlm.nih.gov/pubmed/30038287 http://dx.doi.org/10.1038/s41419-018-0817-1 |
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