Allosteric sodium binding cavity in GPR3: a novel player in modulation of Aβ production

The orphan G-protein coupled receptor 3 (GPR3) belongs to class A G-protein coupled receptors (GPCRs) and is highly expressed in central nervous system neurons. Among other functions, it is likely associated with neuron differentiation and maturation. Recently, GPR3 has also been linked to the produ...

Descripción completa

Detalles Bibliográficos
Autores principales: Capaldi, Stefano, Suku, Eda, Antolini, Martina, Di Giacobbe, Mattia, Giorgetti, Alejandro, Buffelli, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056553/
https://www.ncbi.nlm.nih.gov/pubmed/30038319
http://dx.doi.org/10.1038/s41598-018-29475-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056553/
https://www.ncbi.nlm.nih.gov/pubmed/30038319
http://dx.doi.org/10.1038/s41598-018-29475-7

Ejemplares similares