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Opposite Roles of Wnt7a and Sfrp1 in Modulating Proper Development of Neural Progenitors in the Mouse Cerebral Cortex

The Wingless (Wnt)-mediated signals are involved in many important aspects of development of the mammalian cerebral cortex. How Wnts interact with their modulators in cortical development is still unclear. Here, we show that Wnt7a and secreted frizzled-related protein 1 (Sfrp1), a soluble modulator...

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Detalles Bibliográficos
Autores principales: Miao, Nan, Bian, Shan, Lee, Trevor, Mubarak, Taufif, Huang, Shiying, Wen, Zhihong, Hussain, Ghulam, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056652/
https://www.ncbi.nlm.nih.gov/pubmed/30065628
http://dx.doi.org/10.3389/fnmol.2018.00247