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Human diseases associated with defects in assembly of OXPHOS complexes

The structural biogenesis and functional proficiency of the multiheteromeric complexes forming the mitochondrial oxidative phosphorylation system (OXPHOS) require the concerted action of a number of chaperones and other assembly factors, most of which are specific for each complex. Mutations in a la...

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Detalles Bibliográficos
Autores principales: Ghezzi, Daniele, Zeviani, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056716/
https://www.ncbi.nlm.nih.gov/pubmed/30030362
http://dx.doi.org/10.1042/EBC20170099