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IgG Responses to the Plasmodium falciparum Antigen VAR2CSA in Colombia Are Restricted to Pregnancy and Are Not Induced by Exposure to Plasmodium vivax

Clinical immunity to malaria is associated with the acquisition of IgG specific for members of the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family of clonally variant antigens on the surface of infected erythrocytes (IEs). The VAR2CSA subtype of PfEMP1 mediates IE binding in the...

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Detalles Bibliográficos
Autores principales: Lopez-Perez, Mary, Larsen, Mads Delbo, Bayarri-Olmos, Rafael, Ampomah, Paulina, Stevenson, Liz, Arévalo-Herrera, Myriam, Herrera, Sócrates, Hviid, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056870/
https://www.ncbi.nlm.nih.gov/pubmed/29784859
http://dx.doi.org/10.1128/IAI.00136-18