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miR-22/KAT6B axis is a chemotherapeutic determiner via regulation of PI3k-Akt-NF-kB pathway in tongue squamous cell carcinoma

BACKGROUND: Tongue squamous cell carcinoma (TSCC) is the most common oral cancer. Neoadjuvant systemic treatment before or after surgery for advanced TSCC is considered one of the most crucial factors in reducing mortality. However, the therapeutic benefits of chemotherapy are usually attenuated due...

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Detalles Bibliográficos
Autores principales: Gu, Yixue, Liu, Hao, Kong, Fangren, Ye, Jiahui, Jia, Xiaoting, Zhang, Zhijie, Li, Nan, Yin, Jiang, Zheng, Guopei, He, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056941/
https://www.ncbi.nlm.nih.gov/pubmed/30041677
http://dx.doi.org/10.1186/s13046-018-0834-z