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Role of MCM2–7 protein phosphorylation in human cancer cells

A heterohexameric complex composed of minichromosome maintenance protein 2–7 (MCM2–7), which acts as a key replicative enzyme in eukaryotes, is crucial for initiating DNA synthesis only once per cell cycle. The MCM complex remains inactive through the G1 phase, until the S phase, when it is activate...

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Detalles Bibliográficos
Autores principales: Fei, Liangru, Xu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056998/
https://www.ncbi.nlm.nih.gov/pubmed/30062004
http://dx.doi.org/10.1186/s13578-018-0242-2