Streptococcal M1 protein induces hyporesponsiveness and cytokine release from human arteries in a fibrinogen-dependent manner: a translational study

BACKGROUND: Streptococcus pyogenes is a Gram positive bacterial species commonly involved in sepsis. Invasive strains express virulence factors such as the M1 protein. M1 protein forms complexes with fibrinogen leading to a cytokine storm in plasma contributing to the development of septic shock and...

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Detalles Bibliográficos
Autores principales: Björck, Viveka, Påhlman, Lisa I., Törnebrant, Johan, Bodelsson, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057097/
https://www.ncbi.nlm.nih.gov/pubmed/30041663
http://dx.doi.org/10.1186/s13049-018-0530-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057097/
https://www.ncbi.nlm.nih.gov/pubmed/30041663
http://dx.doi.org/10.1186/s13049-018-0530-1

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