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Lymphopenia-induced proliferation of CD4 T-cells is associated with CD4 T-lymphocyte exhaustion in treated HIV-infected patients

BACKGROUND & OBJECTIVES: Under the lymphopenic condition, T-cells divide to maintain their peripheral pool size. Profound chronic lymphopenia in some treated HIV-infected patients, characterized by poor T-cell recovery, might result in intensive homeostatic proliferation and can cause T-cell exh...

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Detalles Bibliográficos
Autores principales: Saidakova, Evgeniya V., Shmagel, Konstantin V., Korolevskaya, Larisa B., Shmagel, Nadezhda G., Chereshnev, Valeriy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057256/
https://www.ncbi.nlm.nih.gov/pubmed/29998873
http://dx.doi.org/10.4103/ijmr.IJMR_1801_15