PYR-41 and Thalidomide Impair Dendritic Cell Cross-Presentation by Inhibiting Myddosome Formation and Attenuating the Endosomal Recruitments of p97 and Sec61 via NF-κB Inactivation

PYR-41 and thalidomide have therapeutic effects on inflammation-associated diseases with side effects such as tumorigenesis. Cross-presentation allows dendritic cells (DC) to present endogenous antigen and induce protective immunity against microbe infection and tumors. But, up to now, the effects o...

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Detalles Bibliográficos
Autores principales: You, Xiang, Xu, Dan Dan, Zhang, Di, Chen, Jie, Gao, Feng Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057288/
https://www.ncbi.nlm.nih.gov/pubmed/30069488
http://dx.doi.org/10.1155/2018/5070573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057288/
https://www.ncbi.nlm.nih.gov/pubmed/30069488
http://dx.doi.org/10.1155/2018/5070573

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