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MANTA2, update of the Mongo database for the analysis of transcription factor binding site alterations

Interpreting the functional impact of noncoding variants is an ongoing challenge in the field of genome analysis. With most noncoding variants associated with complex traits and disease residing in regulatory regions, altered transcription factor (TF) binding has been proposed as a mechanism of acti...

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Detalles Bibliográficos
Autores principales: Fornes, Oriol, Gheorghe, Marius, Richmond, Phillip A., Arenillas, David J., Wasserman, Wyeth W., Mathelier, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057437/
https://www.ncbi.nlm.nih.gov/pubmed/30040077
http://dx.doi.org/10.1038/sdata.2018.141