Cargando…

Selection analyses of paired HIV-1 gag and gp41 sequences obtained before and after antiretroviral therapy

Most HIV-1-infected individuals with virological failure on a pharmacologically-boosted protease inhibitor (PI) regimen do not develop PI-resistance protease mutations. One proposed explanation is that HIV-1 gag or gp41 cytoplasmic domain mutations might also reduce PI susceptibility. In a recent st...

Descripción completa

Detalles Bibliográficos
Autores principales: Tzou, Philip L., Rhee, Soo-Yon, Pond, Sergei L. Kosakovsky, Manasa, Justen, Shafer, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057438/
https://www.ncbi.nlm.nih.gov/pubmed/30040081
http://dx.doi.org/10.1038/sdata.2018.147