The inhibition of malignant melanoma cell invasion of bone by the TLR7 agonist R848 is dependent upon pro-inflammatory cytokines produced by bone marrow macrophages

Distant metastasis remarkably worsens the prognoses of malignant melanoma patients. Toll-like receptors (TLRs) recognize molecules derived from many types of pathogens and activate the innate intravital immune system. In this study, we examined the effects of R848, a TLR7 ligand, on bone invasion by...

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Detalles Bibliográficos
Autores principales: Manome, Yoko, Suzuki, Dai, Mochizuki, Ayako, Saito, Emi, Sasa, Kiyohito, Yoshimura, Kentaro, Inoue, Tomio, Takami, Masamichi, Inagaki, Katsunori, Funatsu, Takahiro, Kamijo, Ryutaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057452/
https://www.ncbi.nlm.nih.gov/pubmed/30042824
http://dx.doi.org/10.18632/oncotarget.25711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057452/
https://www.ncbi.nlm.nih.gov/pubmed/30042824
http://dx.doi.org/10.18632/oncotarget.25711

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