Anchorage-dependent multicellular aggregate formation induces a quiescent stem-like intractable phenotype in pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal refractory cancers. Aggressive features in PDAC cells have been well studied, but those exhibited by a population of PDAC cells are largely unknown. We show here that coculture with epithelial-like feeder cells confers more malignant...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyatake, Yukiko, Ohta, Yusuke, Ikeshita, Shunji, Kasahara, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057455/
https://www.ncbi.nlm.nih.gov/pubmed/30042817
http://dx.doi.org/10.18632/oncotarget.25732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057455/
https://www.ncbi.nlm.nih.gov/pubmed/30042817
http://dx.doi.org/10.18632/oncotarget.25732

Ejemplares similares