Cargando…
Anchorage-dependent multicellular aggregate formation induces a quiescent stem-like intractable phenotype in pancreatic cancer cells
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal refractory cancers. Aggressive features in PDAC cells have been well studied, but those exhibited by a population of PDAC cells are largely unknown. We show here that coculture with epithelial-like feeder cells confers more malignant...
Autores principales: | Miyatake, Yukiko, Ohta, Yusuke, Ikeshita, Shunji, Kasahara, Masanori |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057455/ https://www.ncbi.nlm.nih.gov/pubmed/30042817 http://dx.doi.org/10.18632/oncotarget.25732 |
Ejemplares similares
-
Visualising the dynamics of live pancreatic microtumours self-organised through cell-in-cell invasion
por: Miyatake, Yukiko, et al.
Publicado: (2018) -
Radiosensitivity of quiescent and proliferating cells grown as multicellular tumor spheroids
por: Onozato, Yusuke, et al.
Publicado: (2017) -
Role of Multicellular Aggregates in Biofilm Formation
por: Kragh, Kasper N., et al.
Publicado: (2016) -
Radiation response of proliferating and quiescent subpopulations isolated from multicellular spheroids.
por: Luk, C. K., et al.
Publicado: (1986) -
A model of quiescent tumour microregions for evaluating multicellular resistance to chemotherapeutic drugs
por: Mellor, H R, et al.
Publicado: (2005)