The regulatory interplay between Oct-1 isoforms contributes to hematopoiesis and the isoforms imbalance correlates with a malignant transformation of B cells

Oct-1(POU2F1) is a DNA-binding transcription regulator and its level being highly increased in many human cancers. Oct-1 is present in the human cells as a family of functionally different isoforms which are transcribed from alternative promoters. Here, we have demonstrated that expression patterns...

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Detalles Bibliográficos
Autores principales: Pankratova, Elizaveta V., Stepchenko, Alexander G., Krylova, Irina D., Portseva, Tatiana N., Georgieva, Sofia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057458/
https://www.ncbi.nlm.nih.gov/pubmed/30042821
http://dx.doi.org/10.18632/oncotarget.25648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057458/
https://www.ncbi.nlm.nih.gov/pubmed/30042821
http://dx.doi.org/10.18632/oncotarget.25648

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