Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated Antigens

Conventional type 1 DCs (cDC1s) excel at cross-presentation of dead cell-associated antigens partly because they express DNGR-1, a receptor that recognizes exposed actin filaments on dead cells. In vitro polymerized F-actin can be used as a synthetic ligand for DNGR-1. However, cellular F-actin is d...

Descripción completa

Detalles Bibliográficos
Autores principales: Schulz, Oliver, Hanč, Pavel, Böttcher, Jan P., Hoogeboom, Robbert, Diebold, Sandra S., Tolar, Pavel, Reis e Sousa, Caetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057488/
https://www.ncbi.nlm.nih.gov/pubmed/29996102
http://dx.doi.org/10.1016/j.celrep.2018.06.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057488/
https://www.ncbi.nlm.nih.gov/pubmed/29996102
http://dx.doi.org/10.1016/j.celrep.2018.06.038

Ejemplares similares