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Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated Antigens

Conventional type 1 DCs (cDC1s) excel at cross-presentation of dead cell-associated antigens partly because they express DNGR-1, a receptor that recognizes exposed actin filaments on dead cells. In vitro polymerized F-actin can be used as a synthetic ligand for DNGR-1. However, cellular F-actin is d...

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Detalles Bibliográficos
Autores principales:	Schulz, Oliver, Hanč, Pavel, Böttcher, Jan P., Hoogeboom, Robbert, Diebold, Sandra S., Tolar, Pavel, Reis e Sousa, Caetano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057488/ https://www.ncbi.nlm.nih.gov/pubmed/29996102 http://dx.doi.org/10.1016/j.celrep.2018.06.038

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