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SVEngine: an efficient and versatile simulator of genome structural variations with features of cancer clonal evolution

BACKGROUND: Simulating genome sequence data with variant features facilitates the development and benchmarking of structural variant analysis programs. However, there are only a few data simulators that provide structural variants in silico and even fewer that provide variants with different allelic...

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Detalles Bibliográficos
Autores principales: Xia, Li Charlie, Ai, Dongmei, Lee, Hojoon, Andor, Noemi, Li, Chao, Zhang, Nancy R, Ji, Hanlee P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057526/
https://www.ncbi.nlm.nih.gov/pubmed/29982625
http://dx.doi.org/10.1093/gigascience/giy081