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Development of a new HPLC method for simultaneous determination of clopidogrel and its major metabolite using a chemometric approach

This paper presents the development and validation of a new HPLC-UV method for simultaneous quantitative determination of clopidogrel and its hydrolysis product clopidogrel carboxylic acid (CCA) from bulk material and dosage formulations. Development of the chromatographic method is based on a desig...

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Detalles Bibliográficos
Autores principales: ANUTA, V., SARBU, I, MIRCIOIU, I, VELESCU, B.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057539/
https://www.ncbi.nlm.nih.gov/pubmed/30151245
http://dx.doi.org/10.12865/CHSJ.41.01.02