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Development of a new HPLC method for simultaneous determination of clopidogrel and its major metabolite using a chemometric approach
This paper presents the development and validation of a new HPLC-UV method for simultaneous quantitative determination of clopidogrel and its hydrolysis product clopidogrel carboxylic acid (CCA) from bulk material and dosage formulations. Development of the chromatographic method is based on a desig...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medical University Publishing House Craiova
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057539/ https://www.ncbi.nlm.nih.gov/pubmed/30151245 http://dx.doi.org/10.12865/CHSJ.41.01.02 |