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Loss of ‘homeostatic’ microglia and patterns of their activation in active multiple sclerosis

Microglia and macrophages accumulate at the sites of active demyelination and neurodegeneration in the multiple sclerosis brain and are thought to play a central role in the disease process. We used recently described markers to characterize the origin and functional states of microglia/macrophages...

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Detalles Bibliográficos
Autores principales: Zrzavy, Tobias, Hametner, Simon, Wimmer, Isabella, Butovsky, Oleg, Weiner, Howard L., Lassmann, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057548/
https://www.ncbi.nlm.nih.gov/pubmed/28541408
http://dx.doi.org/10.1093/brain/awx113