Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays

The protozoan parasite Leishmania causes leishmaniasis; a spectrum of diseases of which there are an estimated 1 million new cases each year. Current treatments are toxic, expensive, difficult to administer, and resistance to them is emerging. New therapeutics are urgently needed, however, screening...

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Detalles Bibliográficos
Autores principales: Berry, Sarah L., Hameed, Hamza, Thomason, Anna, Maciej-Hulme, Marissa L., Saif Abou-Akkada, Somaia, Horrocks, Paul, Price, Helen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057649/
https://www.ncbi.nlm.nih.gov/pubmed/30001317
http://dx.doi.org/10.1371/journal.pntd.0006639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057649/
https://www.ncbi.nlm.nih.gov/pubmed/30001317
http://dx.doi.org/10.1371/journal.pntd.0006639

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