Novel oxazolinoanthracyclines as tumor cell growth inhibitors—Contribution of autophagy and apoptosis in solid tumor cells death

Chemical modification of known, effective drugs are one method to improve the chemotherapy of tumors. We reported ability of oxazoline analogs of doxorubicin (O-DOX) and daunorubicin (O-DAU) to induce apoptosis and autophagy in ovarian and liver cancer cells. Reactive oxygen and nitrogen species (RO...

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Detalles Bibliográficos
Autores principales: Rogalska, Aneta, Gajek, Arkadiusz, Łukawska, Małgorzata, Oszczapowicz, Irena, Marczak, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057680/
https://www.ncbi.nlm.nih.gov/pubmed/30040861
http://dx.doi.org/10.1371/journal.pone.0201296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057680/
https://www.ncbi.nlm.nih.gov/pubmed/30040861
http://dx.doi.org/10.1371/journal.pone.0201296

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