Cargando…

Novel oxazolinoanthracyclines as tumor cell growth inhibitors—Contribution of autophagy and apoptosis in solid tumor cells death

Chemical modification of known, effective drugs are one method to improve the chemotherapy of tumors. We reported ability of oxazoline analogs of doxorubicin (O-DOX) and daunorubicin (O-DAU) to induce apoptosis and autophagy in ovarian and liver cancer cells. Reactive oxygen and nitrogen species (RO...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rogalska, Aneta, Gajek, Arkadiusz, Łukawska, Małgorzata, Oszczapowicz, Irena, Marczak, Agnieszka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057680/ https://www.ncbi.nlm.nih.gov/pubmed/30040861 http://dx.doi.org/10.1371/journal.pone.0201296

Ejemplares similares

Metformin Affects Olaparib Sensitivity through Induction of Apoptosis in Epithelial Ovarian Cancer Cell Lines
por: Gralewska, Patrycja, et al.
Publicado: (2021)

Olaparib-Resistant BRCA2(MUT) Ovarian Cancer Cells with Restored BRCA2 Abrogate Olaparib-Induced DNA Damage and G2/M Arrest Controlled by the ATR/CHK1 Pathway for Survival
por: Biegała, Łukasz, et al.
Publicado: (2023)

Antileukemic activity of novel adenosine derivatives
por: Poczta, Anastazja, et al.
Publicado: (2019)

Participation of the ATR/CHK1 pathway in replicative stress targeted therapy of high-grade ovarian cancer
por: Gralewska, Patrycja, et al.
Publicado: (2020)

Current Implications of microRNAs in Genome Stability and Stress Responses of Ovarian Cancer
por: Gajek, Arkadiusz, et al.
Publicado: (2021)

The Influence of PARP, ATR, CHK1 Inhibitors on Premature Mitotic Entry and Genomic Instability in High-Grade Serous BRCA(MUT) and BRCA(WT) Ovarian Cancer Cells
por: Gralewska, Patrycja, et al.
Publicado: (2022)

Synthesis and In Vitro Activity of Novel Melphalan Analogs in Hematological Malignancy Cells
por: Poczta, Anastazja, et al.
Publicado: (2022)

PARP Inhibition Increases the Reliance on ATR/CHK1 Checkpoint Signaling Leading to Synthetic Lethality—An Alternative Treatment Strategy for Epithelial Ovarian Cancer Cells Independent from HR Effectiveness
por: Gralewska, Patrycja, et al.
Publicado: (2020)

Chemical modification of melphalan as a key to improving treatment of haematological malignancies
por: Gajek, Arkadiusz, et al.
Publicado: (2020)

Subcellular localization of anthracyclines in cultured rat cardiomyoblasts as possible predictors of cardiotoxicity
por: Studzian, Kazimierz, et al.
Publicado: (2015)

Effect of metformin on apoptosis induction in ovarian cancer cells
por: Rogalska, Aneta, et al.
Publicado: (2014)

Two drugs are better than one. A short history of combined therapy of ovarian cancer
por: Bukowska, Barbara, et al.
Publicado: (2014)

Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells
por: Urbańska, Kaja, et al.
Publicado: (2019)

Treatment of Multiple Myeloma and the Role of Melphalan in the Era of Modern Therapies—Current Research and Clinical Approaches
por: Poczta, Anastazja, et al.
Publicado: (2021)

Hyperglycemia-Associated Dysregulation of O-GlcNAcylation and HIF1A Reduces Anticancer Action of Metformin in Ovarian Cancer Cells (SKOV-3)
por: Rogalska, Aneta, et al.
Publicado: (2018)

Newly Synthesized Melphalan Analogs Induce DNA Damage and Mitotic Catastrophe in Hematological Malignant Cancer Cells
por: Poczta, Anastazja, et al.
Publicado: (2022)

Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival
por: Zaarour, Rania F., et al.
Publicado: (2021)

Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells
por: Greenstein, Andrew E., et al.
Publicado: (2021)

At the Crossroads: Mechanisms of Apoptosis and Autophagy in Cell Life and Death
por: Shliapina, V. L., et al.
Publicado: (2021)

Radiation-Induced Autophagy Contributes to Cell Death and Induces Apoptosis Partly in Malignant Glioma Cells
por: Jo, Guk Heui, et al.
Publicado: (2015)

Strange attractors: DAMPs and autophagy link tumor cell death and immunity
por: Hou, W, et al.
Publicado: (2013)

Overcoming resistance to TRAIL-induced apoptosis in solid tumor cells by simultaneously targeting death receptors, c-FLIP and IAPs
por: HUANG, YING, et al.
Publicado: (2016)

Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins
por: Finlay, Darren, et al.
Publicado: (2017)

Role of autophagy in tumor necrosis factor-α-induced apoptosis of osteoblast cells
por: Zheng, Liwen, et al.
Publicado: (2017)

Metastasis and Tumor Cell Migration of Solid Tumors
por: Hoeppner, Jens, et al.
Publicado: (2021)

Autophagy and tumor cell invasion
por: Amaravadi, Ravi K.
Publicado: (2012)

Cell Death Control: The Interplay of Apoptosis and Autophagy in the Pathogenicity of Sclerotinia sclerotiorum
por: Kabbage, Mehdi, et al.
Publicado: (2013)

Alternative Pathways of Cancer Cell Death by Rottlerin: Apoptosis versus Autophagy
por: Torricelli, Claudia, et al.
Publicado: (2012)

Programmed Cell Death in Asthma: Apoptosis, Autophagy, Pyroptosis, Ferroptosis, and Necroptosis
por: Liu, Lu, et al.
Publicado: (2023)

Cell Death Mechanisms in Tumoral and Non-Tumoral Human Cell Lines Triggered by Photodynamic Treatments: Apoptosis, Necrosis and Parthanatos
por: Soriano, J., et al.
Publicado: (2017)

Steroid and Xenobiotic Receptor Signalling in Apoptosis and Autophagy of the Nervous System
por: Wnuk, Agnieszka, et al.
Publicado: (2017)

Utilization of Circulating Tumor Cells in the Management of Solid Tumors
por: Kurniali, Peter C., et al.
Publicado: (2023)

Two Faces of Autophagy in the Struggle against Cancer
por: Chmurska, Anna, et al.
Publicado: (2021)

Mitochondria-Targeting Immunogenic Cell Death Inducer Improves the Adoptive T-Cell Therapy Against Solid Tumor
por: Jiang, Qingzhi, et al.
Publicado: (2019)

Endoplasmic reticulum stress, cell death and tumor: Association between endoplasmic reticulum stress and the apoptosis pathway in tumors
por: Fu, Xiaojing, et al.
Publicado: (2021)

Cell Death and Inflammatory Bowel Diseases: Apoptosis, Necrosis, and Autophagy in the Intestinal Epithelium
por: Nunes, Tiago, et al.
Publicado: (2014)

Davidone C Induces the Death of Hepatocellular Carcinoma Cells by Promoting Apoptosis and Autophagy
por: Song, Ping, et al.
Publicado: (2021)

Programmed Cell Death in Diabetic Nephropathy: A Review of Apoptosis, Autophagy, and Necroptosis
por: Erekat, Nour S.
Publicado: (2022)

Physical modalities inducing immunogenic tumor cell death for cancer immunotherapy
por: Adkins, Irena, et al.
Publicado: (2015)

Revisiting autophagy addiction of tumor cells
por: Nyfeler, Beat, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ep45vggnl0ggm679g3goh31ta2