Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas’ disease drug discovery

Chagas’ disease is responsible for significant mortality and morbidity in Latin America. Current treatments display variable efficacy and have adverse side effects, hence more effective, better tolerated drugs are needed. However, recent efforts have proved unsuccessful with failure of the ergostero...

Descripción completa

Detalles Bibliográficos
Autores principales: MacLean, Lorna M., Thomas, John, Lewis, Michael D., Cotillo, Ignacio, Gray, David W., De Rycker, Manu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057682/
https://www.ncbi.nlm.nih.gov/pubmed/30001347
http://dx.doi.org/10.1371/journal.pntd.0006612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057682/
https://www.ncbi.nlm.nih.gov/pubmed/30001347
http://dx.doi.org/10.1371/journal.pntd.0006612

Ejemplares similares