Drp1 phosphorylation by MAPK1 causes mitochondrial dysfunction in cell culture model of Huntington’s disease

Mitochondrial dysfunction is a major cytopathology in Huntington’s disease (HD), a fatal and inherited neurodegenerative disease. However, the molecular mechanisms by which the disease-causing gene, mutant Huntingtin (mtHtt), affects mitochondrial function remains elusive. This study aims to determi...

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Detalles Bibliográficos
Autores principales: Roe, Anne Jessica, Qi, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057844/
https://www.ncbi.nlm.nih.gov/pubmed/29397067
http://dx.doi.org/10.1016/j.bbrc.2018.01.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057844/
https://www.ncbi.nlm.nih.gov/pubmed/29397067
http://dx.doi.org/10.1016/j.bbrc.2018.01.114

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