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Synergistic antibacterial activity of silver with antibiotics correlating with the upregulation of the ROS production

Thiol-dependent enzymes, including the thioredoxin (Trx) and glutathione (GSH) systems, have recently been found as promising bactericidal targets in multidrug-resistant (MDR) bacteria. We previously discovered that silver acted synergistically with ebselen in the inhibition of the Trx system and al...

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Detalles Bibliográficos
Autores principales: Zou, Lili, Wang, Jun, Gao, Yu, Ren, Xiaoyuan, Rottenberg, Martin E., Lu, Jun, Holmgren, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057937/
https://www.ncbi.nlm.nih.gov/pubmed/30042429
http://dx.doi.org/10.1038/s41598-018-29313-w