Evaluating the bromodomain protein BRD1 as a therapeutic target in rheumatoid arthritis

Targeting epigenetic reader proteins by small molecule inhibitors represents a new therapeutic concept in autoimmune diseases such as rheumatoid arthritis (RA). Although inhibitors targeting bromodomain protein 1 (BRD1) are in development, the function of BRD1 has hardly been studied. We investigate...

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Detalles Bibliográficos
Autores principales: Klein, Kerstin, Kato, Masaru, Frank-Bertoncelj, Mojca, Kolling, Christoph, Ciurea, Adrian, Gay, Steffen, Ospelt, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057939/
https://www.ncbi.nlm.nih.gov/pubmed/30042400
http://dx.doi.org/10.1038/s41598-018-29127-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057939/
https://www.ncbi.nlm.nih.gov/pubmed/30042400
http://dx.doi.org/10.1038/s41598-018-29127-w

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