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Evaluating the bromodomain protein BRD1 as a therapeutic target in rheumatoid arthritis
Targeting epigenetic reader proteins by small molecule inhibitors represents a new therapeutic concept in autoimmune diseases such as rheumatoid arthritis (RA). Although inhibitors targeting bromodomain protein 1 (BRD1) are in development, the function of BRD1 has hardly been studied. We investigate...
Autores principales: | Klein, Kerstin, Kato, Masaru, Frank-Bertoncelj, Mojca, Kolling, Christoph, Ciurea, Adrian, Gay, Steffen, Ospelt, Caroline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057939/ https://www.ncbi.nlm.nih.gov/pubmed/30042400 http://dx.doi.org/10.1038/s41598-018-29127-w |
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