Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer

The cellular and molecular basis of stromal cell recruitment, activation and crosstalk in carcinomas is poorly understood, limiting the development of targeted anti-stromal therapies. In mouse models of triple negative breast cancer (TNBC), Hedgehog ligand produced by neoplastic cells reprograms can...

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Detalles Bibliográficos
Autores principales: Cazet, Aurélie S., Hui, Mun N., Elsworth, Benjamin L., Wu, Sunny Z., Roden, Daniel, Chan, Chia-Ling, Skhinas, Joanna N., Collot, Raphaël, Yang, Jessica, Harvey, Kate, Johan, M. Zahied, Cooper, Caroline, Nair, Radhika, Herrmann, David, McFarland, Andrea, Deng, Niantao, Ruiz-Borrego, Manuel, Rojo, Federico, Trigo, José M., Bezares, Susana, Caballero, Rosalía, Lim, Elgene, Timpson, Paul, O’Toole, Sandra, Watkins, D. Neil, Cox, Thomas R., Samuel, Michael S., Martín, Miguel, Swarbrick, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057940/
https://www.ncbi.nlm.nih.gov/pubmed/30042390
http://dx.doi.org/10.1038/s41467-018-05220-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057940/
https://www.ncbi.nlm.nih.gov/pubmed/30042390
http://dx.doi.org/10.1038/s41467-018-05220-6

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