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Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity

Functional circuit assembly is thought to require coordinated development of excitation and inhibition, but whether they are co-regulated cell-autonomously remains unclear. We investigate effects of decreased glutamatergic synaptic input on inhibitory synapses by expressing AMPAR subunit, GluA1 and...

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Detalles Bibliográficos
Autores principales: He, Hai-yan, Shen, Wanhua, Zheng, Lijun, Guo, Xia, Cline, Hollis T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057951/
https://www.ncbi.nlm.nih.gov/pubmed/30042473
http://dx.doi.org/10.1038/s41467-018-05125-4