The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors

Zika virus is a global health threat due to significantly elevated risk of fetus malformations in infected pregnant women. Currently, neither an effective therapy nor a prophylactic vaccination is available for clinical use, desperately necessitating novel therapeutics and approaches to obtain them....

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Detalles Bibliográficos
Autores principales: Šebera, Jakub, Dubankova, Anna, Sychrovský, Vladimír, Ruzek, Daniel, Boura, Evzen, Nencka, Radim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057956/
https://www.ncbi.nlm.nih.gov/pubmed/30042483
http://dx.doi.org/10.1038/s41598-018-29459-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057956/
https://www.ncbi.nlm.nih.gov/pubmed/30042483
http://dx.doi.org/10.1038/s41598-018-29459-7

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