An acidic model pro-peptide affects the secondary structure, membrane interactions and antimicrobial activity of a crotalicidin fragment

In order to study how acidic pro-peptides inhibit the antimicrobial activity of antimicrobial peptides, we introduce a simple model system, consisting of a 19 amino-acid long antimicrobial peptide, and an N-terminally attached, 10 amino-acid long acidic model pro-peptide. The antimicrobial peptide i...

Descripción completa

Detalles Bibliográficos
Autores principales: Júnior, Nelson G. O., Cardoso, Marlon H., Cândido, Elizabete S., van den Broek, Daniëlle, de Lange, Niek, Velikova, Nadya, Kleijn, J. Mieke, Wells, Jerry M., Rezende, Taia M. B., Franco, Octávio Luiz, de Vries, Renko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057973/
https://www.ncbi.nlm.nih.gov/pubmed/30042491
http://dx.doi.org/10.1038/s41598-018-29444-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057973/
https://www.ncbi.nlm.nih.gov/pubmed/30042491
http://dx.doi.org/10.1038/s41598-018-29444-0

Ejemplares similares