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An acidic model pro-peptide affects the secondary structure, membrane interactions and antimicrobial activity of a crotalicidin fragment
In order to study how acidic pro-peptides inhibit the antimicrobial activity of antimicrobial peptides, we introduce a simple model system, consisting of a 19 amino-acid long antimicrobial peptide, and an N-terminally attached, 10 amino-acid long acidic model pro-peptide. The antimicrobial peptide i...
Autores principales: | Júnior, Nelson G. O., Cardoso, Marlon H., Cândido, Elizabete S., van den Broek, Daniëlle, de Lange, Niek, Velikova, Nadya, Kleijn, J. Mieke, Wells, Jerry M., Rezende, Taia M. B., Franco, Octávio Luiz, de Vries, Renko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057973/ https://www.ncbi.nlm.nih.gov/pubmed/30042491 http://dx.doi.org/10.1038/s41598-018-29444-0 |
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