Durable targeting of B-lymphocytes in living mice

Transfer to and enduring expression of genes in B cells has proved a vexing challenge. We report here a novel method for the specific and durable targeting of B lymphocytes in living mice. The method involves generation of lentiviruses pseudotyped with an anti-CD19 antibody. CD19 targeting viruses i...

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Detalles Bibliográficos
Autores principales: Cascalho, M., Huynh, D., Lefferts, A. R., Stein, L., Lanigan, T., Decker, J., Shea, L. D., Platt, J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057982/
https://www.ncbi.nlm.nih.gov/pubmed/30042489
http://dx.doi.org/10.1038/s41598-018-29452-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057982/
https://www.ncbi.nlm.nih.gov/pubmed/30042489
http://dx.doi.org/10.1038/s41598-018-29452-0

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