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Induction of protein aggregation in zebrafish embryos as a method for the screening of new drugs or mutations against proteinopathies
The sustained increase in the prevalence of protein aggregation related diseases requires the development of feasible methods for the design of therapeutic alternatives. The procedure traditionally used for the search of drugs or therapeutic mutations includes in vitro experiments, designed to preve...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058008/ https://www.ncbi.nlm.nih.gov/pubmed/30046518 http://dx.doi.org/10.1016/j.mex.2018.04.004 |