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Induction of protein aggregation in zebrafish embryos as a method for the screening of new drugs or mutations against proteinopathies

The sustained increase in the prevalence of protein aggregation related diseases requires the development of feasible methods for the design of therapeutic alternatives. The procedure traditionally used for the search of drugs or therapeutic mutations includes in vitro experiments, designed to preve...

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Detalles Bibliográficos
Autores principales: Lobos-Ruiz, Pablo, Araya, Gissela, Monasterio, Octavio, Pouchucq, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058008/
https://www.ncbi.nlm.nih.gov/pubmed/30046518
http://dx.doi.org/10.1016/j.mex.2018.04.004