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Single Cell T Cell Receptor Sequencing: Techniques and Future Challenges

The peculiarity of T cell is their ability to recognize an infinite range of self and foreign antigens. This ability is achieved during thymic development through a complex molecular mechanism based on somatic recombination that leads to the expression of a very heterogeneous population of surface a...

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Detalles Bibliográficos
Autores principales: De Simone, Marco, Rossetti, Grazisa, Pagani, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058020/
https://www.ncbi.nlm.nih.gov/pubmed/30072991
http://dx.doi.org/10.3389/fimmu.2018.01638