Structural Lipids Enable the Formation of Functional Oligomers of the Eukaryotic Purine Symporter UapA

The role of membrane lipids in modulating eukaryotic transporter assembly and function remains unclear. We investigated the effect of membrane lipids in the structure and transport activity of the purine transporter UapA from Aspergillus nidulans. We found that UapA exists mainly as a dimer and that...

Descripción completa

Detalles Bibliográficos
Autores principales: Pyle, Euan, Kalli, Antreas C., Amillis, Sotiris, Hall, Zoe, Lau, Andy M., Hanyaloglu, Aylin C., Diallinas, George, Byrne, Bernadette, Politis, Argyris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058078/
https://www.ncbi.nlm.nih.gov/pubmed/29681524
http://dx.doi.org/10.1016/j.chembiol.2018.03.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058078/
https://www.ncbi.nlm.nih.gov/pubmed/29681524
http://dx.doi.org/10.1016/j.chembiol.2018.03.011

Ejemplares similares