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LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion

Monocyte adhesion is a crucial step in transmigration and can be induced by lipopolysaccharide (LPS). Here, we studied the role of mammalian target of rapamycin (mTOR) complexes, mTORC1 and mTORC2, and PKC in this process. We used THP-1 cells, a human monocytic cell line, to investigate monocyte adh...

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Detalles Bibliográficos
Autores principales: Ribeiro, Marcelle C., Peruchetti, Diogo B., Silva, Leandro S., Silva-Filho, João L., Souza, Mariana C., Henriques, Maria das Graças, Caruso-Neves, Celso, Pinheiro, Ana Acacia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058081/
https://www.ncbi.nlm.nih.gov/pubmed/30073169
http://dx.doi.org/10.3389/fmolb.2018.00067