Cargando…
LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion
Monocyte adhesion is a crucial step in transmigration and can be induced by lipopolysaccharide (LPS). Here, we studied the role of mammalian target of rapamycin (mTOR) complexes, mTORC1 and mTORC2, and PKC in this process. We used THP-1 cells, a human monocytic cell line, to investigate monocyte adh...
Autores principales: | Ribeiro, Marcelle C., Peruchetti, Diogo B., Silva, Leandro S., Silva-Filho, João L., Souza, Mariana C., Henriques, Maria das Graças, Caruso-Neves, Celso, Pinheiro, Ana Acacia S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058081/ https://www.ncbi.nlm.nih.gov/pubmed/30073169 http://dx.doi.org/10.3389/fmolb.2018.00067 |
Ejemplares similares
-
Lithium ameliorates tubule-interstitial injury through activation of the mTORC2/protein kinase B pathway
por: Teixeira, Douglas E., et al.
Publicado: (2019) -
mTORC1 and mTORC2 in cancer and the tumor microenvironment
por: Kim, Laura C., et al.
Publicado: (2016) -
Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension
por: Tang, Haiyang, et al.
Publicado: (2018) -
mTORC1 Enhances Early Phase Ribosome Processivity
por: An, Erin, et al.
Publicado: (2020) -
Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion
por: Chen, Long, et al.
Publicado: (2015)