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The reversal effect of prothrombin complex concentrate (PCC), activated PCC and recombinant activated factor VII in apixaban‐treated patients in vitro

ESSENTIALS: An antidote for apixaban is not yet available. We tested the effect of different haemostatic agents to reverse the apixaban effect in vitro. Activated prothrombin complex concentrate (aPCC) was superior to prothrombin complex concentrate and recombinant activated factor VII. Even low dos...

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Detalles Bibliográficos
Autores principales: Schultz, Nina H., Tran, Hoa T. T., Bjørnsen, Stine, Henriksson, Carola E., Sandset, Per M., Holme, Pål A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058213/
https://www.ncbi.nlm.nih.gov/pubmed/30046673
http://dx.doi.org/10.1002/rth2.12015