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Semi-Mechanism-Based Pharmacodynamic Model for the Anti-Inflammatory Effect of Baicalein in LPS-Stimulated RAW264.7 Macrophages

Monitoring of the inhibition of TNF-α, IL-6, iNOS, and NO is used to effectively evaluate anti-inflammatory drugs. Baicalein was found to have good anti-inflammatory activities, but its detailed cellular pharmacodynamic events have not been expatiated by any other study. The inflammatory mediators,...

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Detalles Bibliográficos
Autores principales: Xiang, Li, Hu, Ying-Fan, Wu, Jia-Si, Wang, Li, Huang, Wen-Ge, Xu, Chen-Si, Meng, Xian-Li, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058255/
https://www.ncbi.nlm.nih.gov/pubmed/30072902
http://dx.doi.org/10.3389/fphar.2018.00793