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Assessment of the effect of direct oral anticoagulants dabigatran, rivaroxaban, and apixaban in healthy male volunteers using a thrombin generation assay

ESSENTIALS: The value of thrombin generation assay (TGA) in monitoring direct oral anticoagulants (DOAC) is not well defined. TGA parameters were measured and correlated to DOAC levels in 10 healthy volunteers after oral intake of DOACs. Lag time is the only sensitive TGA parameter across different...

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Detalles Bibliográficos
Autores principales: Artang, Ramin, Anderson, Maren, Riley, Paul, Nielsen, Jorn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058270/
https://www.ncbi.nlm.nih.gov/pubmed/30046690
http://dx.doi.org/10.1002/rth2.12044