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Assessment of the effect of direct oral anticoagulants dabigatran, rivaroxaban, and apixaban in healthy male volunteers using a thrombin generation assay
ESSENTIALS: The value of thrombin generation assay (TGA) in monitoring direct oral anticoagulants (DOAC) is not well defined. TGA parameters were measured and correlated to DOAC levels in 10 healthy volunteers after oral intake of DOACs. Lag time is the only sensitive TGA parameter across different...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058270/ https://www.ncbi.nlm.nih.gov/pubmed/30046690 http://dx.doi.org/10.1002/rth2.12044 |