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MicroRNA-217 attenuates intima–media complex thickness of ascending aorta measured by ultrasound bio-microscopy and inhibits inflammation and lipid metabolism in atherosclerotic models of ApoE(−/−) mice
BACKGROUND: Little investigation was done to test the efficiency of microRNA-217 (miR-217) on atherosclerosis in vivo. METHODS: ApoE(−/−) mice were used to construct atherosclerotic models and ultrasound bio-microscopy (UBM) was applied to detect the intima–media thickness (IMT) of the ascending aor...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058357/ https://www.ncbi.nlm.nih.gov/pubmed/30041636 http://dx.doi.org/10.1186/s12944-018-0825-2 |