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Single-cell transcriptome analysis of lineage diversity in high-grade glioma

BACKGROUND: Despite extensive molecular characterization, we lack a comprehensive understanding of lineage identity, differentiation, and proliferation in high-grade gliomas (HGGs). METHODS: We sampled the cellular milieu of HGGs by profiling dissociated human surgical specimens with a high-density...

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Detalles Bibliográficos
Autores principales: Yuan, Jinzhou, Levitin, Hanna Mendes, Frattini, Veronique, Bush, Erin C., Boyett, Deborah M., Samanamud, Jorge, Ceccarelli, Michele, Dovas, Athanassios, Zanazzi, George, Canoll, Peter, Bruce, Jeffrey N., Lasorella, Anna, Iavarone, Antonio, Sims, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058390/
https://www.ncbi.nlm.nih.gov/pubmed/30041684
http://dx.doi.org/10.1186/s13073-018-0567-9